Adams, M.D., Celniker, S.E., Holt, R.A. et al. (2000) The genome sequence of Drosophila melanogaster. Science 287, 2185-2195. Altschul, S.F., Madden, T.L., Schaffer, A.A. et al. (1997) Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Research 25, 3389-3402. Ashburner, M. and Bergman, C.M. (2005) Drosophila mela-nogaster: a case study of a model genomic sequence and its consequences. Genome Research 15, 1661-1667. Barillas-Mury, C. (2007) CLIP proteases and Plasmodium melanization in Anopheles gambiae. Trends in Parasitology 23, 297-299.

Bent, A.F. and Mackey, D. (2007) Elicitors, effectors, and R genes: the new paradigm and a lifetime supply of questions. Annual Review of Phytopathology 45, 399-436. Blandin, S. and Levashina, E.A. (2004) Thioester-containing proteins and insect immunity. Molecular Immunology 40, 903-908. Blandin, S., Shiao, S.H., Moita, L.F. et al. (2004) Complement-like protein TEP1 is a determinant of vectorial capacity in the malaria vector Anopheles gambiae. Cell 116, 661-670. Christophides, G.K., Zdobnov, E. , Barillas-Mury, C. et al. (2002) Immunity-related genes and gene families in Anopheles gambiae. Science 298, 159-165.

Christophides, G.K., Vlachou, D., and Kafatos, F.C. (2004) Comparative and functional genomics of the innate immune system in the malaria vector Anopheles gambiae. Immunological Reviews 198, 127-148.

Clark, A.G., Eisen, M.B., Smith, D.R. et al. (2007) Evolution of genes and genomes on the Drosophila phylogeny. Nature 450, 203-218.

Cohuet, A., Osta, M.A., Morlais, I. et al. (2006) Anopheles and Plasmodium: from laboratory models to natural systems in the field. EMBO Reports 7, 1285-1289.

Dimopoulos, G., Christophides, G.K., Meister, S. et al. (2002) Genome expression analysis of Anopheles gambiae: responses to injury, bacterial challenge, and malaria infection. Proceedings of the National Academy of Sciences USA 99, 8814-8819.

Dostert, C., Jouanguy, E., Irving, P. et al. (2005) The JakSTAT signaling pathway is required but not sufficient for the antiviral response of Drosophila. Nature Immunology 6, 946-53.

Eddy, S.R. (1998) Profile hidden Markov models. Bioinformatics 14, 755-763.

Evans, J.D., Aronstein, K., Chen, Y.P. et al. (2006) Immune pathways and defence mechanisms in honey bees Apis mellifera. Insect Molecular Biology 15, 645-656.

Fenerjian, M.G. and Kafatos, F.C. (1994) Developmental specificity of a bidirectional moth chorion promoter in transgenic Drosophila. Developmental Biology 161, 37-47.

Habtewold, T., Povelones, M., Blagborough, A. et al. (2008) Transmission blocking immunity in the malaria non-vector mosquito Anopheles quadriannulatus species A. PLoS Pathogens 4, e1000070.

HGSC (2006) Insights into social insects from the genome of the honeybee Apis mellifera. Nature 443, 931-949.

Holt, R.A., Subramanian, G.M., Halpern, A. et al. (2002) The genome sequence of the malaria mosquito Anopheles gambiae. Science 298, 129-149.

Kocks, C., Cho, J.H., Nehme, N. et al. (2005) Eater, a transmembrane protein mediating phagocytosis of bacterial pathogens in Drosophila. Cell 123, 335-346.

Koonin, E.V. (2005) Orthologs, paralogs, and evolutionary genomics. Annual Review of Genetics 39, 309-338.

Kriventseva, E.V., Rahman, N., Espinosa, O., and Zdobnov, E.M. (2008) OrthoDB: the hierarchical catalog of eukaryotic orthologs. Nucleic Acids Research 36, D271-D275.

Kurucz, E., Markus, R., Zsámboki, J. et al. (2007) Nimrod, a putative phagocytosis receptor with EGF repeats in Drosophila plasmatocytes. Current Biology 17, 649-654.

Lemaitre, B. and Hoffmann, J. (2007) The host defense of Drosophila melanogaster. Annual Review of Immunology 25, 697-743.

Leulier, F. and Lemaitre, B. (2008) Toll-like receptors taking an evolutionary approach. Nature Reviews Genetics 9, 165-178.

Levashina, E.A., Moita, L.F., Blandin, S. et al. (2001) Conserved role of a complement-like protein in phagocytosis revealed by dsRNA knockout in cultured cells of the mosquito, Anopheles gambiae. Cell 104, 709-718.

Li, J.S., Ruyl Kim, S., Christensen, B.M., and Li, J. (2005) Purification and primary structural characterization of prophenoloxidases from Aedes aegypti larvae. Insect Biochemistry and Molecular Biology 35, 1269-1283.

Lin, M.F., Deoras, A.N., Rasmussen, M.D., and Kellis, M. (2008) Performance and scalability of discriminative metrics for comparative gene identification in 12 Drosophila genomes. PLoS Computational Biology 4, e1000067.

Manaka, J., Kuraishi, T., Shiratsuchi, A. et al. (2004) Draper-mediated and phosphatidylserine-independent phagocytosis of apoptotic cells by Drosophila hemo-cytes/macrophages. Journal of Biological Chemistry 279, 48466-48476.

Mangahas, P.M. and Zhou, Z. (2005) Clearance of apop-totic cells in Caenorhabditis elegans. Seminars in Cell and Developmental Biology 16, 295-306.

Martinez-Cruzado, J.C., Swimmer, C., Fenerjian, M.G., and Kafatos, F.C. (1988) Evolution of the autosomal chorion locus in Drosophila. I. General organization of the locus and sequence comparisons of genes s15 and s19 in evolutionary distant species. Genetics 119, 663-677.

Mitsialis, S.A., Spoerel, N., Leviten, M., and Kafatos, F.C. (1987) A short 5'-flanking DNA region is sufficient for developmentally correct expression of moth chorion genes in Drosophila. Proceedings of the National Academy of Sciences USA 84, 7987-7991.

Moita, L.F., Wang-Sattler, R., Michel, K. et al. (2005) In vivo identification of novel regulators and conserved pathways of phagocytosis in A. gambiae. Immunity 23, 65-73.

Nene, V., Wortman, J.R., Lawson, D. et al. (2007) Genome sequence of Aedes aegypti, a major arbovirus vector. Science 316, 1718-1723.

Osta, M.A., Christophides, G.K., Vlachou, D., and Kafatos, F.C. (2004) Innate immunity in the malaria vector Anopheles gambiae: comparative and functional genomics. Journal of Experimental Biology 207, 2551-2563.

Pancer, Z., Amemiya, C.T., Erhardt, G. et al. (2004) Somatic diversification of variable lymphocyte receptors in the agnathan sea lamprey. Nature 430, 174-180.

Paskewitz, S.M., Andreev, O., and Shi, L. (2006) Gene silencing of serine proteases affects melanization of Sephadex beads in Anopheles gambiae. Insect Biochemistry and Molecular Biology 36, 701-711.

Povelones, M., Waterhouse, R.M., Kafatos, F.C. & Christophides, G.K. (2009) Leucine-rich repeat protein complex activates mosquito complement in defense against Plasmodium parasites. Science DOI: 10.1126/ science. 1171400.

Riehle, M.M., Markianos, K., Niare, O. et al. (2006) Natural malaria infection in Anopheles gambiae is regulated by a single genomic control region. Science 312, 577-579.

Riehle, M.M., Xu, J., Lazarro, B.P. (2008) Anopheles gambiae APL1 is a family of variable LRR proteins required for Rel1-mediated protection from the malaria parasite, Plasmodium berghei. PLoS ONE, 3, e3672.

Ruan, J., Li, H., Chen, Z. et al. (2008) TreeFam: 2008 Update. Nucleic Acids Research 36, D735-D740.

Sackton, T.B., Lazzaro, B.P., Schlenke, T.A. et al. (2007) Dynamic evolution of the innate immune system in Drosophila. Nature Genetics 39, 1461-1468.

Savard, J., Tautz, D., Richards, S. et al. (2006) Phylogenomic analysis reveals bees and wasps (Hymenoptera) at the base of the radiation of Holometabolous insects. Genome Research 16, 1334-1338.

Shaw, M.H., Reimer, T., Kim, Y., and Nunez, G. (2008) NOD-like receptors (NLRs): bona fide intracellular microbial sensors. Current Opinions in Immunology 20, 377-382.

Sinden, R.E., Alavi, Y., and Raine, J.D. (2004) Mosquito-malaria interactions: a reappraisal of the concepts of susceptibility and refractoriness. Insect Biochemistry and Molecular Biology 34, 625-629.

Somogyi, K., Sipos, B., Penzes, Z. et al. (2008) Evolution of genes and repeats in the Nimrod superfamily. Molecular Biology and Evolution 25, 2337-2347.

Stark, A., Lin, M.F., Kheradpour, P. et al. (2007) Discovery of functional elements in 12 Drosophila genomes using evolutionary signatures. Nature 450, 219-232.

Steiner, H., Hultmark, D., Engström, A. et al. (1981) Sequence and specificity of two antibacterial proteins involved in insect immunity. Nature 292, 246-248.

Sun, S.C., Lindstrom, I., Lee, J.Y., and Faye, I. (1991) Structure and expression of the attacin genes in Hyalophora cecropia. European Journal of Biochemistry 196, 247-254.

TGSC (2008) The genome of the model beetle and pest Tribolium castaneum. Nature 452, 949-955.

Vlachou, D. and Kafatos, F.C. (2005) The complex interplay between mosquito positive and negative regulators of Plasmodium development. Current Opinions in Microbiology 8, 415-421.

Volz, J., Osta, M.A., Kafatos, F.C., and Muller, H.M. (2005) The roles of two clip domain serine proteases in innate immune responses of the malaria vector Anopheles gam-biae. Journal of Biological Chemistry 280, 40161-40168.

Volz, J., Muller, H.M., Zdanowicz, A. et al. (2006) A genetic module regulates the melanization response of Anopheles to Plasmodium. Cellular Microbiology 8, 1392-1405.

von Frisch, K. (1974) Decoding the language of the bee. Science 185, 663-668.

Wang, L., Weber, A.N., Atilano, M.L. et al. (2006) Sensing of Gram-positive bacteria in Drosophila: GNBP1 is needed to process and present peptidoglycan to PGRP-SA. EMBO Journal 25, 5005-5014.

Wapinski, I., Pfeffer, A., Friedman, N., and Regev, A. (2007) Automatic genome-wide reconstruction of phylogenetic gene trees. Bioinformatics 23, i549-i558.

Warr, E., Das, S., Dong, Y., and Dimopoulos, G. (2008) The Gram-negative bacteria-binding protein gene family: its role in the innate immune system of Anopheles gam-biae and in anti-Plasmodium defence. Insect Molecular Biology 17, 39-51.

Waterhouse, R.M., Kriventseva, E.V., Meister, S. et al. (2007) Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes. Science 316, 1738-1743.

Wyder, S., Kriventseva, E.V., Schröder, R. et al. (2007) Quantification of ortholog losses in insects and vertebrates. Genome Biology 8, R242.

Xia, Q., Zhou, Z., Lu, C. et al. (2004) A draft sequence for the genome of the domesticated silkworm (Bombyx mori). Science 306, 1937-1940.

Zdobnov, E.M. and Apweiler, R. (2001) InterProScan--an integration platform for the signature-recognition methods in InterPro. Bioinformatics 17, 847-848.

Zdobnov, E.M. and Bork, P. (2007) Quantification of insect genome divergence. Trends in Genetics 23, 16-20.

Zdobnov, E.M., von Mering, C., Letunic, I. et al. (2002) Comparative genome and proteome analysis of Anopheles gambiae and Drosophila melanogaster. Science 298, 149-159.


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