We can all visualize streams so full of suspended material that the water is opaque, and where no visible life could possibly exist. This represents an extreme case of high solids loading. Any natural water will contain some suspended solids, but often the material is of such a small particle size that it cannot be easily seen. It is only when you look at two samples of water, one of which you consider 'clean' and the other which has been filtered to sub-micron level, that you can see the difference. The filtered water glistens, while the 'clean' water suddenly looks distinctly dirty. Even if the particles are chemically inert, their physical properties could cause problems.
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