Use of combinations of ecotoxicological models in a modeling system will likely increase in the future. The Across-Trophic-Level System Simulation (ATLSS) is a landscape model of the Everglades in the state of Florida in the US. ATLSS is a multicomponent modeling framework or set of integrated models that simulate the hierarchy of whole-system responses across all trophic levels and across spatial and temporal scales that are ecologically relevant to a large wetland system. ATLSS uses different modeling approaches tailored to each trophic level, including differential equations for process models of lower levels and age-structured and individualbased models for higher levels. Other integrated modeling systems exist that include an eutrophication model, a toxic chemical fate and transport model, a toxicity model, and a food-web model.
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