AQUATOX is a simulation model for aquatic ecosystems developed under the auspices of the US EPA. The model predicts the fate of various stressors, such as nutrients, organic chemicals, and invasive species, and their effects on aquatic ecosystems, including those consisting of fish, invertebrates, and aquatic plants. Provided below is a case study example to describe the use of AQUATOX in the assessment of potential aquatic ecosystem-level effects associated with the use of permethrin. Permethrin is a synthetic pyrethroid that is most often aerially applied to areas surrounding water to control adult mosquitoes. Permethrin is used by vector control agencies in several eastern US states to control mosquito-borne pathogens, such as West Nile virus (WNV) and eastern equine encephalomyelitis virus (EEE).
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