Empirical Facts

It has been known for long, and is a generally accepted fact now, that mutations with major (deleterious) fitness effects are almost always recessive. In the simplest case of two alleles, A and a, at a locus, the fitness of the three possible genotypes, AA, Aa, and aa, are usually denoted by 1,1 — hs, 1 — s. Here, s is the selection coefficient and h the dominance coefficient. A mutant is neutral if s = 0 and lethal if s = 1. If h = 0, then A is dominant and a is recessive; if h = 1, then a is dominant and A recessive; if h = V, one says there is no dominance; if 0< h <1, one speaks of intermediate dominance or codominance; if h <0, then there is overdominance, whereas underdominance prevails if h > 1.

Was this article helpful?

0 0
Oplan Termites

Oplan Termites

You Might Start Missing Your Termites After Kickin'em Out. After All, They Have Been Your Roommates For Quite A While. Enraged With How The Termites Have Eaten Up Your Antique Furniture? Can't Wait To Have Them Exterminated Completely From The Face Of The Earth? Fret Not. We Will Tell You How To Get Rid Of Them From Your House At Least. If Not From The Face The Earth.

Get My Free Ebook


Post a comment