Fish

Field studies of wild fish populations provide evidence that dioxin-like action compounds may be impacting early life stage survival in the environment. An early development edematous syndrome prior to death has been described in Salmo salar sac fry where the suspected eliciting agents were PCDDs and PCDFs. In lake trout (Salvelinus namaycush) sac fry from Lake Ontario, an increased incidence of blue-sac disease, consisting of a yolk sac edema and hemorrhages, has been found, and retrospectively linked to PCDD and PCDF exposure. In the laboratory, many studies on fish developmental toxi-city show that very low TCDD concentrations elicit similar effects in newly fertilized fish eggs and sac fry.

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