All four serotypes of dengue viruses (DEN-1, DEN-2, DEN-3, DEN-4) are endemic in Thailand (Nisalak et al. 2003). However, the predominant virus serotypes which have been frequently associated with epidemics vary from year to year. According to the data collected between 1973 and 1999 from 15,376 dengue patients admitted in the Queen Sirikit National Institute of Child Health (formerly the Bangkok Children's Hospital) in Bangkok, DEN-2 was predominant from 1973 to 1986 and 1988 to 1989; DEN-3 in 1987, and from 1995 to 1999; DEN-1 from 1990 to 1992; and DEN-4 from 1993 to 1994 (Nisalak et al. 2003). Among 50 isolations of dengue viruses obtained from DHF patients admitted at the Rayong Provincial Hospital from 1980 to 1984, DEN-2 was the predominant serotype (46%), followed by DEN-1 (32%), DEN-4 (12%) and DEN-3 (10%), respectively (Rojanasuphot et al. 1988). Recently, Anantapreecha et al. (2005) found that 45% out of 2,715 confirmed specimens collected from six hospitals scattered throughout Thailand between 1999 and 2002 were identified as DEN-1, whereas the rest were DEN-2 (32%), DEN-3 (18%) and DEN-4 (5%), respectively.
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